BCR-ABL Positive Chronic Myelogenous Leukemia

Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Also Known As:

Chronic Myelogenous Leukemia; Chronic Myeloid Leukemia; Leukemia, Chronic Myelogenous; Leukemia, Chronic Myeloid; Leukemia, Myeloid, Philadelphia Positive; Chronic Granulocytic Leukemia; Myeloid Leukemia, Chronic; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myelogenous, Ph1 Positive; Leukemia, Myelogenous, Ph1-Positive; Leukemia, Myeloid, Ph1 Positive; Leukemia, Myeloid, Ph1-Positive; Leukemia, Myeloid, Philadelphia-Positive; Myelogenous Leukemia, Ph1-Positive; Myeloid Leukemia, Ph1-Positive; Myeloid Leukemia, Philadelphia-Positive; Chronic Granulocytic Leukemias; Chronic Myelocytic Leukemia; Chronic Myelocytic Leukemias; Chronic Myelogenous Leukemias; Chronic Myeloid Leukemias; Granulocytic Leukemias, Chronic; Leukemia, Chronic Granulocytic; Leukemia, Chronic Myelocytic; Leukemia, Ph1-Positive Myelogenous; Leukemia, Ph1-Positive Myeloid; Leukemia, Philadelphia-Positive Myeloid; Leukemias, Chronic Granulocytic; Leukemias, Chronic Myelocytic; Leukemias, Chronic Myelogenous; Leukemias, Chronic Myeloid; Leukemias, Ph1-Positive Myelogenous; Leukemias, Ph1-Positive Myeloid; Leukemias, Philadelphia-Positive Myeloid; Myelocytic Leukemias, Chronic; Myelogenous Leukemia, Ph1 Positive; Myelogenous Leukemias, Chronic; Myelogenous Leukemias, Ph1-Positive; Myeloid Leukemia, Ph1 Positive; Myeloid Leukemia, Philadelphia Positive; Myeloid Leukemias, Chronic; Myeloid Leukemias, Ph1-Positive; Myeloid Leukemias, Philadelphia-Positive; Ph1-Positive Myelogenous Leukemia; Ph1-Positive Myelogenous Leukemias; Ph1-Positive Myeloid Leukemia; Ph1-Positive Myeloid Leukemias; Philadelphia-Positive Myeloid Leukemia; Philadelphia-Positive Myeloid Leukemias; Granulocytic Leukemia, Chronic; Leukemia, Granulocytic, Chronic; Leukemia, Myelocytic, Chronic; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Chronic; Myelocytic Leukemia, Chronic; Myelogenous Leukemia, Chronic

Neoplasms: 1361496
- Neoplasms by Histologic Type: 2
  - Leukemia: 59371
    - Myeloid Leukemia: 4065
      - BCR-ABL Positive Chronic Myelogenous Leukemia: 14646
Hemic and Lymphatic Diseases: 7
- Hematologic Diseases: 3445
  - Leukemia: 59371
    - Myeloid Leukemia: 4065
      - BCR-ABL Positive Chronic Myelogenous Leukemia: 14646
  - Bone Marrow Diseases: 139
    - Myeloproliferative Disorders: 1425
      - BCR-ABL Positive Chronic Myelogenous Leukemia: 14646
Signs and Symptoms Pathological Conditions
- Pathologic Processes: 10385
  - Disease Attributes: 18
    - Chronic Disease: 26704
      - BCR-ABL Positive Chronic Myelogenous Leukemia: 14646

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Disease

Drug/Important Bio-Agent (IBA)